Some generalized symptoms include fever , fatigue , weight loss or loss of appetite , shortness of breath , anemia, easy bruising or bleeding, petechiae flat, pin-head sized spots under the skin caused by bleeding , bone and joint pain, and persistent or frequent infections. How well treatment works also depends on other factors, including the number of white blood cells. Bone marrow aspiration , blood test . Am J Epidemiol.
World Health Organization (WHO) classification of AML
In Virchow R ed. Acute leukemias of ambiguous lineage also known as mixed phenotype or biphenotypic acute leukemia occur when the leukemic cells can not be classified as either myeloid or lymphoid cells, or where both types of cells are present. For example, the acute promyelocytic leukemia APL subtype is often treated using drugs that are different from those used for other subtypes of AML. Cleveland Clinic Journal of Medicine.